ABSTRACT
Periconceptional care such as lifestyle plays an important impact role in offspring health. The aim of the present study was to clarify the perspective of Avicenna on periconceptional care. Avicenna (980-1037 A.D.) was one of the outstanding Persian physicians, who made great contributions to the field of medical sciences, in particular, obstetrics. In advance, Avicenna's book, Canon of Medicine, was considered to find his perspectives on periconceptional care. Then, his ideas and theories were compared to the current findings by searching the keywords in main indexing systems including PubMed/MEDLINE, Scopus and Institute for Scientific Information Web of Science as well as the search engine of Google Scholar. Current investigations show that gamete quality, pregnancy outcome, and offspring health at birth and long term depend on both parents' lifestyle in pre- and periconceptional period, as well as the intrauterine environment. Avicenna believed that seminal fluid, sperm, ovum, and developing conditions in utero were influenced by the stages of food digestion and the function of some organs. On the other hand, food digestion and function of the organs also depend on each parent's lifestyle and environmental factors. He mentioned 6 principles of healthy lifestyle: exercise, nutrition, sleep and awareness, excretion of body wastes and retention of necessary materials, psychic features, as well as air and climate. Thus, a multicomponent healthy lifestyle should be considered by parents of child-bearing age in an appropriate period before and in early pregnancy as well as elimination of any disorders in parents, to give birth to more healthy offspring.
ABSTRACT
Burn injury is one of the most destructive events in the world. The Pergularia tomentosa L. is a medicinal plant that traditionally, applies for treatment of burning, in Bushehr province, Iran. Various bioactive compounds such as steroid glycosides, tannins, various vitamins, saponins, cardenolides and anthraquinones were identified into extract of the plant, which can be effective in burn wound healing. Twenty-one rats weighting every one 200+/-5 grams were divided equally into three groups. The second-degree burning induced on all groups. One of groups did not receive any treatment [The control group] and was treated locally with saline and eucerin. The Second group received the P. tomentosa L. as a topical ointment, and the third group received locally, a thin layer of silver sulfadiazine ointment 3% after washing the wound with saline. Afterward treatment period, the microscopic slides from histological sections were prepared. At that point, amounts of the fibroblast cells, blood vessels, wound area, necrotic tissues, and diameter of epidermis rate of wound healing were determined. Also the exterior status of wound in different days was considered. Results obtained from current study have revealed that the extract of P. tomentosa L. can significantly, cause qualitative and quantitative acceleration in healing of second degree burn wounds, due to their bioactive and vasoactive properties. In conclusion the P. tomentosa L. can is used as an overborne medicine with lower cost and side effect than the similar chemical medicines. Although, the further studies are needed on these plants, due to their some toxic effects
ABSTRACT
Appendicitis is one of the most common surgical emergencies. In spite of the relatively high rate of negative appendectomy, as a result of miss diagnosis, uncertainty of diagnosis still continues to challenge physicians. The objective of this prospective study was to investigate the role of [99m]Tc-Ubiquicidin [UBI] scintigraphy in the diagnosis of acute appendicitis and to compare [99m]Tc-UBI scintigraphy with [99m]Tc-IgG scintigraphy. Twelve patients with right lower quadrant pain and suspicious of acute appendicitis were referred to the nuclear medicine imaging center. Radionuclide imaging was performed with [99m]Tc-UBI in 8 and [99m]Tc-IgG in 4 patients. Ultrasonography, Alvarado scoring and histopathological examinations were also performed as additional diagnostic tests. Reports from [99m]Tc-IgG and [99m]Tc-UBI scintigraphies of all patients were negative. This study may conclude that [99m]Tc-IgG scintigraphy and [99m]Tc-UBI scintigraphy in the detection of appendicitis do not have adequate efficacy. However, in order to better evaluate [99m]Tc-IgG and [99m]Tc-UBI scintigraphy, a comprehensive study on a large number of patients with clinical suspicious of acute appendicitis would be more helpful
ABSTRACT
The principle of cancer immunotherapy includes various methods of manipulations to influence immune responses against tumors in both humans and animals. This advanced technology of hybridoma production provided the necessary skills to efficiently produce highly specific monoclonal antibodies [mAb]. Radioactively-tagged antibodies which are applied in radioimmunotherapy [RIT], can target adjacent cells and may not require immune function. This study highlights the mechanism and the effect of action of radioimmunotherapic agents, especially two applied agents including [90]Yibritumomab tiuxetan and [131]I-tositumomab that are approved by Food and Drug Administration [FDA] for treatment of some cancers
Subject(s)
Humans , Antibodies, Monoclonal , Yttrium Radioisotopes , Neoplasms/therapyABSTRACT
Mental health is one of the evaluating factors of community indicators, and physical activity is considered an important tool for the importance of public health. Previous studies have demonstrated associations between physical activity and mental health, but these studies did not include those populations in which training children have some traditional and religious aspects. Multiple logistic regression analyses were used to compare the prevalence of mental health among those who had inactive, minimally and HEPA activity in a representative sample of adolescents aged 15-19 in South of Iran using data from the Mental Health Survey [n = 2584]. The GHQ-28 and IPAQ-short forms were used to evaluate the mental health and physical activity, respectively. A total of 2584 adolescents [1401 male and 1178 female] participated in the study. The observed odds of psychological symptoms in boys compared to girls is 1.2 times [p=0.018]. We observed that HEPA-activity decreases odds of somatic distress and social dysfunction compared with inactivity [p=0.031 and 0.001, respectively]; minimally activity decreases odds of anxiety compared with inactivity [p=0.038]; but physical activity rate was not affected on odds of adolescents' depression [p>0.05]. Physical activity decreases mental health subscales except for depression among adolescents in Boushehr, southern city of Iran